Introduction
Because of its presence in popular drinks, caffeine is doubtlessly the most widely consumed of all behaviorally active drugs Serafin, 1996 Fredholm et al., 1999 . Although caffeine is the major pharmacologically active methylxanthine in coffee and tea, cocoa and chocolate contain severalfold higher levels of theobromine than caffeine, along with trace amounts of theophylline. Paraxanthine is a major metabolite of caffeine in humans, while theophylline is a minor metabolite. Thus, not only...
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